| Identification | Back Directory | [Name]
SJ000291942 | [CAS]
425613-09-8 | [Synonyms]
SJ000291942
SJ000291942 >=98% (HPLC)
Acetamide, 2-(4-ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)- | [Molecular Formula]
C16H15FN2O4 | [MDL Number]
MFCD02219567 | [MOL File]
425613-09-8.mol | [Molecular Weight]
318.3 |
| Chemical Properties | Back Directory | [Boiling point ]
525.4±50.0 °C(Predicted) | [density ]
1.327±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml | [form ]
A crystalline solid | [pka]
11.44±0.70(Predicted) | [color ]
White to off-white | [InChI]
1S/C16H15FN2O4/c1-2-11-3-6-13(7-4-11)23-10-16(20)18-12-5-8-14(17)15(9-12)19(21)22/h3-9H,2,10H2,1H3,(H,18,20) | [InChIKey]
YSZJLXPXVFGTNK-UHFFFAOYSA-N | [SMILES]
CCC1=CC=C(OCC(NC2=CC([N+]([O-])=O)=C(F)C=C2)=O)C=C1 |
| Hazard Information | Back Directory | [Uses]
2-(4-Ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)acetamide is a canonical bone morphogenetic proteins (BMP) signaling pathway activator. | [Biological Activity]
SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value < 1 μM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilagebut are now considered to constitute a group of pivotal morphogenetic signalsorchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryosactivate SMAD1/5/8 phosphorylationand induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation. |
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| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
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