| Identification | Back Directory | [Name]
PROSTAGLANDIN H2 | [CAS]
42935-17-1 | [Synonyms]
PGH2
PGR2
GPR142
ENDOPEROXIDE H2
PROSTAGLANDIN R2
PROSTAGLANDIN H2
PGH2 (Prostaglandin H2)
[1-14C]Prostaglandin?H2
Prostaglandin?H2?(PGH2)
PROSTAGLANDIN H2 SOLUTION
G-protein coupled receptor PGR2
Probable G-protein coupled receptor 142
Endoperoxide H2, PGH2, Prostaglandin R2
ANTI-GPR142(N-TERMINAL) antibody produced in rabbit
Prostaglandin H2,Endoperoxide H2, PGH2, Prostaglandin R2
9ALPHA,11ALPHA-EPIDIOXY-15S-HYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID
(5Z,13E,15S)-9α,11α-Epidioxy-15-hydroxyprosta-5,13-dien-1-oic acid
Prosta-5,13-dien-1-oic acid, 9,11-epidioxy-15-hydroxy-, (5Z,9α,11α,13E,15S)-
7-[5-(3-hydroxyoct-1-enyl)-2,3-dioxabicyclo[2.2.1]hept-6-yl]hept-5-enoic acid
(Z)-7-[(1S,2R,3S,4R)-3-[(E,3S)-3-hydroxyoct-1-enyl]-5,6-dioxabicyclo[2.2.1]hept-2-yl]hept-5-enoic acid | [EINECS(EC#)]
200-662-2 | [Molecular Formula]
C20H32O5 | [MDL Number]
MFCD00036972 | [MOL File]
42935-17-1.mol | [Molecular Weight]
352.47 |
| Chemical Properties | Back Directory | [Boiling point ]
490.1±40.0 °C(Predicted) | [density ]
1.129±0.06 g/cm3(Predicted) | [Fp ]
-17 °C | [storage temp. ]
−70°C | [solubility ]
Ethanol: >100 mg/ml; PBS pH 7.2: >2 mg/ml | [form ]
acetone solution | [pka]
4.76±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor. PGH2 is the precursor for all 2-series PGs and thromboxanes (TXs), and is a TP receptor agonist which irreversibly aggregates human platelets at 50-100 ng/ml. | [Uses]
PGH2 (Prostaglandin H2) is a thromboxane A2 precursor and a platelet aggregator of vascular smooth muscle contraction. | [Definition]
ChEBI: Prostaglandin H2 is an oxylipin, an olefinic compound, a secondary alcohol and a prostaglandins H. It has a role as a mouse metabolite. It is a conjugate acid of a prostaglandin H2(1-). | [References]
[1] M HAMBERG. Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1974, 71 2: 345-349. DOI: 10.1073/pnas.71.2.345
[2] KATE?INA MACáKOVá . In vitro platelet antiaggregatory properties of 4-methylcoumarins[J]. Biochimie, 2012, 94 12: Pages 2681-2686. DOI: 10.1016/j.biochi.2012.09.006 |
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