| Identification | Back Directory | [Name]
Sulfisoxazole Diolamine | [CAS]
4299-60-9 | [Synonyms]
Diethanolamine salt
Sulfisoxazole diolamine
Sulfisoxazole diethanolamine
SULFISOXAZOLE DIOLAMINE (500 MG) DISCONTINUED
N-(3,4-dimethylisoxazol-5-yl)sulphanilamide, compound with 2,2'-iminodiethanol (1:1) | [EINECS(EC#)]
224-308-1 | [Molecular Formula]
C13H15N3O4S.C4H11NO2 | [MOL File]
4299-60-9.mol | [Molecular Weight]
414.48 |
| Hazard Information | Back Directory | [Uses]
Antibacterial. | [Definition]
ChEBI: An organoammonium salt obtained by combining equimolar amounts of sulfisoxazole and diethanolamine. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms. | [Brand name]
Gantrisin (Roche). | [General Description]
Sulfisoxazole diolamine is described with the short- and intermediate-acting sulfonamides and also used in intravenousand intramuscular preparations. | [Clinical Use]
4-Amino-N-(3,5-dimethyl-5-isoxazolyl)benzenesulfonamidecompound with 2,2 -iminobis[ethanol](1:1); 2,2 -iminodiethanol salt of N1-(3,4-dimethyl-5-isoxazolyl)sulfanilamide.This salt is prepared by adding enoughdiethanolamine to a solution of sulfisoxazole to bring thepH to about 7.5. It is used as a salt to make the drug moresoluble in the physiological pH range of 6.0 to 7.5 and isused in solution for systemic administration of the drug byslow intravenous, intramuscular, or subcutaneous injectionwhen high enough blood levels cannot be maintained byoral administration alone. It also is used for instillation ofdrops or ointment in the eye for the local treatment of susceptibleinfections. |
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