| Identification | Back Directory | [Name]
VITAMIN E NICOTINATE | [CAS]
43119-47-7 | [Synonyms]
renascin
Ve Nicotinate
VitaminEnicotihat
Vitamin E nicotinate
tocopherylnicotinate
vitaminenicotinicacidester
ALPHA-TOCOPHERYL NICOTINATE
D-alpha-Tocopheryl nicotinate
VITAMIN E NICOTINATE USP/EP/BP
5,7,8-Trimethyltocol nicotinate
VITAMIN E NICOTINATE (TOCOTHERYL NICOTINATE)
(2r-(2r*(4r*,8r*)))-ridecyl)-2h-1-benzopyran-6-yleste
[2theta-[2theta(4theta,8theta)]]-ridecyl)-2h-1-benzopyran-6-yleste
(+/-)-2,5,7,8-tetramethyl-2-(4,8,12 (-trimethyltridecyl)chromanol nicotinate
3-pyridinecarboxylicacid,3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethylt
[2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)CHROMAN-6-YL] PYRIDINE-3-CARBOXYLATE
(R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol nicotinate
[2R-[2R*(4R*,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl nicotinate
[2r*(4r*,8r*)]-(+/-)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-yl nicotinate
Nicotinic acid (R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl ester
3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ylester,[2R-[2R*(3-Pyridinecarboxylicacid
3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-ylester,(2r-(2r*(4r3-pyridinecarboxylicaci
3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- benzopyran-6-yl ester, [2R-[2R*(3-Pyridinecarboxylic acid
3-Pyridinecarboxylic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4R,8R)-4,8,12-trimethyltridecyl-2H-1-benzopyran-6-yl ester
3-Pyridinecarboxylic acid, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran -6-yl ester, [2R-[2R(4R,8R)]]- | [EINECS(EC#)]
256-101-7 | [Molecular Formula]
C35H53NO3 | [MDL Number]
MFCD00057302 | [MOL File]
43119-47-7.mol | [Molecular Weight]
535.8 |
| Chemical Properties | Back Directory | [Boiling point ]
649.0±55.0 °C(Predicted) | [density ]
0.990±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [pka]
3.03±0.10(Predicted) | [Cosmetics Ingredients Functions]
SKIN PROTECTING
SKIN CONDITIONING
ANTIOXIDANT | [LogP]
11.327 (est) |
| Hazard Information | Back Directory | [Uses]
Vitamin E nicotinate is the derivative of Vitamin E. Vitamin E nicotinate exhibits antioxidant activity and prevents lipid peroxidation. Vitamin E nicotinate upregulates levels of CD4+ T cells and IL-2, exhibits immunomodulatory activity. Vitamin E nicotinate exhibits antiplatelet and antihypertensive activities, that can be used in atherosclerosis and thrombosis ressearch[1]. | [Definition]
ChEBI: Tocopheryl nicotinate is a tocol. | [Synthesis]
To a three-necked flask add 250g of dichloromethane, add 50g of nicotinic acid, 43.9g of N,N'-carbonyl diimidazole, 30 ° C reaction for 2 hours, take 122.5g of tocopherol dissolved in 150g of dichloromethane, and then dropwise added to the reaction system | [References]
[1] Duncan KR, et al., Vitamin E Nicotinate. Antioxidants (Basel). 2017 Mar 13;6(1):20. DOI:10.3390/antiox6010020 |
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