| Identification | Back Directory | [Name]
ethyl 4-[(1r,4r)-4-{[(2S)-2-hydroxy-3-(4-hydroxy-3-methanesulfonamidophenoxy)propyl]amino}cyclohexyl]benzoate hydrochloride | [CAS]
433212-21-6 | [Synonyms]
SAR-150640
ethyl 4-[(1r,4r)-4-{[(2S)-2-hydroxy-3-(4-hydroxy-3-methanesulfonamidophenoxy)propyl]amino}cyclohexyl]benzoate hydrochloride | [EINECS(EC#)]
694-842-1 | [Molecular Formula]
C25H35ClN2O7S | [MOL File]
433212-21-6.mol | [Molecular Weight]
543.073 |
| Hazard Information | Back Directory | [Uses]
SAR-150640, a selective β3-adrenoceptor agonist, prevents the increase in MMP activity and production observed after LPS stimulation or in cases of chorioamnionitis[1]. | [IC 50]
β3 adrenoceptor | [References]
[1] F Lirussi, et al. SAR150640, a selective beta3-adrenoceptor agonist, prevents human myometrial remodelling and activation of matrix metalloproteinase in an in vitro model of chorioamnionitis. Br J Pharmacol. 2010 Mar;159(6):1354-66. DOI:10.1111/j.1476-5381.2009.00616.x |
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