| Identification | Back Directory | [Name]
β-Alanine, N-[(3-methylphenyl)methyl]-N-[(3-phenoxyphenyl)methyl]- | [CAS]
434910-94-8 | [Synonyms]
PC58538
PC58538 Sodium
β-Alanine, N-[(3-methylphenyl)methyl]-N-[(3-phenoxyphenyl)methyl]- | [Molecular Formula]
C24H25NO3 | [MOL File]
434910-94-8.mol | [Molecular Weight]
375.47 |
| Hazard Information | Back Directory | [Description]
PC58538 inhibitor of FtsZ protein, a key player in the division machinery of bacterial cells. | [Uses]
PC58538 is a cell division inhibitor, targeting to FtsZ. PC58538 shows moderate antibacterial activity, and inhibits cell division in vegetative cells of wild-type B. subtilis. PC58538 is also known to modulate the rate of GTP hydrolysis[1][2]. | [References]
[1] Stokes NR, et al. Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay. J Biol Chem. 2005 Dec 2;280(48):39709-15. DOI:10.1074/jbc.M506741200 |
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