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436846-91-2

436846-91-2 Structure

436846-91-2 Structure
IdentificationBack Directory
[Name]

D-erythro-sphinganine-1-phosphate (C20 base)
[CAS]

436846-91-2
[Synonyms]

Sphinganine-1-Phosphate (d20:0)
D-erythro-sphinganine-1-phosphate (C20 base)
1,3-Eicosanediol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R)-
D-ERYTHRO-SPHINGANINE-1-PHOSPHATE (C20 BASE);SPHINGANINE-1-PHOSPHATE (D20:0)
[Molecular Formula]

C20H44NO5P
[MDL Number]

MFCD22416904
[MOL File]

436846-91-2.mol
[Molecular Weight]

409.54
Chemical PropertiesBack Directory
[Boiling point ]

569.0±60.0 °C(Predicted)
[density ]

1.060±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

powder
[pka]

1.76±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Sphinganine-C20-1-phosphate is lethal to saccharomyces cerevisiae cells when accumulated thus may be used to regulate yeast cell growth.
[General Description]

Sphinganine-1-Phosphate is a phosphorylated derivative of C20 base sphinganine.
[Biochem/physiol Actions]

Exogenous sphinganine-1-phosphate activates sphingosine-1-phosphate receptor 1 (S1P1). It exhibits protective effects against hepatic and renal ischemia and reperfusion (IR). Sphingosine-1 phosphate and sphinganine-1-phosphate are bioactive lipid mediators. Sphinganine-1-phosphate acts opposite to sphingosine-1 phosphate activities. Increased concentration of sphinganine-1-phosphate acts as a potential biomarker for fumonisin exposure and toxicity in mice.
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