| Identification | Back Directory | [Name]
1-{4-[(4-ethoxyphenoxy)methyl]benzoyl}-3-methylpiperidine | [CAS]
438474-67-0 | [Synonyms]
WAY-325462
Antitrypanosomal agent 9
1-{4-[(4-ethoxyphenoxy)methyl]benzoyl}-3-methylpiperidine
(4-((4-Ethoxyphenoxy)methyl)phenyl)(3-methylpiperidin-1-yl)methanone | [Molecular Formula]
C22H27NO3 | [MOL File]
438474-67-0.mol | [Molecular Weight]
353.455 |
| Hazard Information | Back Directory | [Uses]
Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory activity against T. b. brucei, with an IC50 of 1.15 μM. Antitrypanosomal agent 9 can be used for human African trypanosomiasis (HAT) research[1]. | [IC 50]
Trypanosoma | [References]
[1] Manos-Turvey Alexandra, et al. Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents. Med Chem Commun. 2015, 6(3), 403–406. |
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