ChemicalBook--->CAS DataBase List--->440327-45-7

440327-45-7

440327-45-7 Structure

440327-45-7 Structure
IdentificationBack Directory
[Name]

3'-O-Levulinyl-2'-deoxyadenosine
[CAS]

440327-45-7
[Synonyms]

3'-O-Levulinyl-2'-deoxyadenosine
2'-Deoxyadenosine-3'-(4-oxopentanoate)
2'-Deoxy-3'-O-(4-oxopentanoyl)adenosine
3’-O-Levulinyl-2’-deoxyadenosine, 2’-Deoxyadenosine-3’-(4-oxopentanoate)
[Molecular Formula]

C15H19N5O5
[MOL File]

440327-45-7.mol
[Molecular Weight]

349.34
Chemical PropertiesBack Directory
[Boiling point ]

640.7±65.0 °C(Predicted)
[density ]

1.63±0.1 g/cm3(Predicted)
[pka]

14.44±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

3’-O-Levulinyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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