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442644-28-2

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442644-28-2 Structure

442644-28-2 Structure
IdentificationBack Directory
[Name]

JW67
[CAS]

442644-28-2
[Synonyms]

JW67
Trispiro JW67
JW67 >=98% (HPLC)
trispiro[indoline-3,2-1,3-dioxane-5,5-1,3-dioxane-2,3-indoline]-2,23-dione
Trispiro[3H-indole-3,2'-[1,3]dioxane-2'',3'''-[3H]indole]-2,2'''(1H,1'''H)-dione
Trispiro[3H-indole-3,2′-[1,3]dioxane-5′,5′′-[1,3]dioxane-2′′,3′′′-[3H]indole]-2,2′′′(1H,1′′′H)-dione (9CI)
[Molecular Formula]

C21H18N2O6
[MDL Number]

MFCD03036757
[MOL File]

442644-28-2.mol
[Molecular Weight]

394.38
Chemical PropertiesBack Directory
[Boiling point ]

728.6±60.0 °C(Predicted)
[density ]

1.54±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: >5mg/mL
[form ]

powder
[pka]

13.39±0.20(Predicted)
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P301+P310
[Hazard Codes ]

T
[Risk Statements ]

25
[Safety Statements ]

45
[RIDADR ]

UN 2811 6.1 / PGIII
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

JW 67 is a novel synthetic antagonist of canonical Wnt signaling and inhibits growth and downregulated Wnt target genes in human colorectal cancer cells.
[storage]

Store at +4°C
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