| Identification | Back Directory | [Name]
N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide | [CAS]
443292-81-7 | [Synonyms]
SF 11
SID 17507305
SF-11 >=98% (HPLC)
N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide
N-(4-ethoxyphenyl)-4-(hydroxydiphenylMethyl)piperidine-1-carbothioaMide
1-Piperidinecarbothioamide, N-(4-ethoxyphenyl)-4-(hydroxydiphenylmethyl)- | [Molecular Formula]
C27H30N2O2S | [MDL Number]
MFCD03032390 | [MOL File]
443292-81-7.mol | [Molecular Weight]
446.6 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at +4°C | [solubility ]
DMSO: ≥20mg/mL | [form ]
powder | [color ]
white to off-white | [InChI]
1S/C27H30N2O2S/c1-2-31-25-15-13-24(14-16-25)28-26(32)29-19-17-23(18-20-29)27(30,21-9-5-3-6-10-21)22-11-7-4-8-12-22/h3-16,23,30H,2,17-20H2,1H3,(H,28,32) | [InChIKey]
PMEQBGAGFZDWQX-UHFFFAOYSA-N | [SMILES]
CCOc1ccc(NC(=S)N2CCC(CC2)C(O)(c3ccccc3)c4ccccc4)cc1 |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H319 | [Precautionary statements ]
P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
36 | [Safety Statements ]
26 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Uses]
SF 11 is a selective brain penetrant neuropeptide Y Y2 receptor antagonist. | [Definition]
ChEBI: N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide is a diarylmethane. | [Biological Activity]
Radioligand studies reveal th at SF-11 also targets 5-HT2B and dopamine transporter.1''SF-11 is a potentselective NPY Y2 receptor antagonist; brain-penetrant. | [IC 50]
NPY Y2 receptor: 199 nM (IC50) | [storage]
Store at +4°C |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|