| Identification | Back Directory | [Name]
N-(4-anilinophenyl)-4-tert-butylbenzamide | [CAS]
443639-96-1 | [Synonyms]
S119-8
S119-8 >=98% (HPLC)
Influenza inhibitor S119-8
N-(4-anilinophenyl)-4-tert-butylbenzamide
4-tert-Butyl-N-(4-phenylamino-phenyl)-benzamide
N-(4-anilinophenyl)-4-tert-butylbenzamide (S119-8)
4-(1,1-Dimethylethyl)-N-[4-(phenylamino)phenyl]benzamide
Benzamide, 4-(1,1-dimethylethyl)-N-[4-(phenylamino)phenyl]-
Influenza Virus,S-119-8,viruses,S119-8,spectrum,S119 8,inhibit,Inhibitor,influenza,S1198 | [Molecular Formula]
C23H24N2O | [MDL Number]
MFCD01121291 | [MOL File]
443639-96-1.mol | [Molecular Weight]
344.45 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO : ≥ 150 mg/mL (435.48 mM) | [form ]
powder | [color ]
white to beige | [InChIKey]
NEPKMQDGCTXOPG-UHFFFAOYSA-N | [SMILES]
O=C(C1=CC=C(C(C)(C)C)C=C1)NC2=CC=C(NC3=CC=CC=C3)C=C2 |
| Hazard Information | Back Directory | [Uses]
S119-8 is a broad spectrum inhibitor of influenza A and B viruses, showing activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus, but does not inhibit a non-influenza virus, vesicular stomatitis nirus (VSV)[1]. | [Biological Activity]
S119-8 is an inhibitor of viral nucleoprotein of influenza A and B. It showed synergistic effects with oseltamivir. | [References]
[1] White KM, et al. Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein. ACS Infect Dis. 2018 Feb 9;4(2):146-157. DOI:10.1021/acsinfecdis.7b00120 |
|
| Company Name: |
Twochem Co.Ltd.
|
| Telephone: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
|