| Identification | Back Directory | [Name]
7-Iodo-7-deaza-D-guanosine | [CAS]
444020-71-7 | [Synonyms]
7-Deaza-7-iodoguanosine
7-Iodo-7-deaza-D-guanosine
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-
2-Amino-3,7-dihydro-5-iodo-7-beta-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one | [Molecular Formula]
C11H13IN4O5 | [MOL File]
444020-71-7.mol | [Molecular Weight]
408.15 |
| Hazard Information | Back Directory | [Uses]
2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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