| Identification | Back Directory | [Name]
L-Alanine, N-[2,6-dichloro-4-[[[(2E)-3-(2-furanyl)-1-oxo-2-propen-1-yl]amino]methyl]benzoyl]-3-[[(4R)-4-thiazolidinylcarbonyl]amino]- | [CAS]
444169-80-6 | [Synonyms]
ICAM1988
ICAM-1988
ICAM 1988
L-Alanine, N-[2,6-dichloro-4-[[[(2E)-3-(2-furanyl)-1-oxo-2-propen-1-yl]amino]methyl]benzoyl]-3-[[(4R)-4-thiazolidinylcarbonyl]amino]- | [Molecular Formula]
C22H22Cl2N4O6S | [MOL File]
444169-80-6.mol | [Molecular Weight]
541.4 |
| Hazard Information | Back Directory | [Uses]
ICAM-1988 is a small molecule lymphocyte function-associated antigen-1 (LFA-1) antagonist that disrupts the LFA-1/ICAM-1 interaction and has anti-inflammatory activity[1]. | [References]
[1] Khojasteh SC, et al. Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug. Xenobiotica. 2008 Mar;38(3):340-52. DOI:10.1080/00498250701813248 |
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