| Identification | Back Directory | [Name]
1H-Indole, 6-[[(2R)-2-[2-[4-(4-chlorophenoxy)-1-piperidinyl]ethyl]-1-pyrrolidinyl]sulfonyl]- | [CAS]
446020-51-5 | [Synonyms]
SB656104
SB-656104
SB 656104
SB-656104A
1H-Indole, 6-[[(2R)-2-[2-[4-(4-chlorophenoxy)-1-piperidinyl]ethyl]-1-pyrrolidinyl]sulfonyl]- | [Molecular Formula]
C25H30ClN3O3S | [MDL Number]
MFCD07363966 | [MOL File]
446020-51-5.mol | [Molecular Weight]
488.04 |
| Hazard Information | Back Directory | [Uses]
SB-656104 is a potent antagonist of 5-HT7 receptor, with the pKi of 8.70, blocking 5-carboxamidotryptamine (5-CT) stimulated adenylyl cyclase activity[1]. | [References]
[1] Ian T Forbes, et al. SB-656104-A: a novel 5-HT7 receptor antagonist with improved in vivo properties. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3341-4. DOI:10.1016/s0960-894x(02)00690-x |
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