| Identification | Back Directory | [Name]
1-octanoyl-2-hydroxy-sn-glycero-3-phosphocholine | [CAS]
45287-18-1 | [Synonyms]
LPC (8:0)
1-octanoyl-2-hydroxy-sn-glycero-3-phosphocholine
1-OCTANOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE;08:0 LYSO PC | [Molecular Formula]
C16H34NO7P | [MOL File]
45287-18-1.mol | [Molecular Weight]
383.42 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
powder | [pka]
1.197±0.50(predicted) | [InChIKey]
ZVPMBHRQDPDKEF-OAHLLOKOSA-N | [SMILES]
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCC)=O |
| Hazard Information | Back Directory | [Uses]
08:0 Lyso PC (1-Octanoyl-sn-glycero-3-phosphocholine) is a lysolecithin that can be hydrolyzed by Phospholipase A2 (HY-P3029)[1]. | [Definition]
ChEBI: 1-octanoyl-sn-glycero-3-phosphocholine zwitterion is an organic molecular entity and a 1-O-acyl-sn-glycero-3-phosphocholine. It is functionally related to an octanoate. | [Biological Activity]
Lysophosphatidylcholine (Lyso-PC) is linked to inflammatory diseases and atherosclerosis. It enhances the expression of genes for growth factors and cellular adhesion molecules. | [References]
[1] Lee CH, et al. A binding study of phospholipase A2 with lecithin, lysolecithin and their tetrahedral intermediates using molecular modeling. J Pept Res. 1997 Jul;50(1):25-33. DOI:10.1111/j.1399-3011.1997.tb00616.x |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
|
| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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