| Identification | Back Directory | [Name]
7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6-dihydro- | [CAS]
4546-73-0 | [Synonyms]
8-Aza-2’-deoxyguanosine
8-Aza-2’-deoxyguanosine
7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6-dihydro- | [Molecular Formula]
C9H12N6O4 | [MOL File]
4546-73-0.mol | [Molecular Weight]
268.23 |
| Hazard Information | Back Directory | [Uses]
8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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