| Identification | Back Directory | [Name]
4'-METHYLCHRYSOERIOL | [CAS]
4712-12-3 | [Synonyms]
4'-METHYLCHRYSOERIOL
CHRYSOERIOL 4'-O-METHYL ETHER
Luteolin 3',4'-dimethyl ether
Luteolin-3',4'-dimethyl ether
Rutoside Trihydrate Impurity 13
5,7-DIHYDROXY-3',4'-DIMETHOXYFLAVONE
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,7-dihydroxy- | [Molecular Formula]
C17H14O6 | [MDL Number]
MFCD00017422 | [MOL File]
4712-12-3.mol | [Molecular Weight]
314.29 |
| Chemical Properties | Back Directory | [Melting point ]
244 °C (decomp)(Solv: methanol (67-56-1)) | [Boiling point ]
538.3±50.0 °C(Predicted) | [density ]
1.402±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 20.83 mg/mL (66.28 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
6.49±0.40(Predicted) | [color ]
Light yellow to yellow | [InChI]
InChI=1S/C17H14O6/c1-21-13-4-3-9(5-15(13)22-2)14-8-12(20)17-11(19)6-10(18)7-16(17)23-14/h3-8,18-19H,1-2H3 | [InChIKey]
AOLOMULCAJQEIG-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=C(OC)C(OC)=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1 | [LogP]
2.970 (est) |
| Hazard Information | Back Directory | [Description]
5,7-Dihydroxy-3‘,4’-dimethoxyflavone, also known as 4'-Methylchrysoeriol , is a bioactive Flavonoids found in plants such as Eupatorium odoratum. Studies have shown that 4'-Methylchrysoeriol has death receptor 5 promoter-enhancing activity. | [Uses]
4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. | [Biological Activity]
4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. | [storage]
Store at -20°C | [References]
[1] Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res To DOI:10.1021/tx900127s |
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| Company Name: |
parabiochem
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025-83453382-8005 |
| Website: |
www.parabiochem.cn |
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