| Identification | Back Directory | [Name]
3'-Hydroxypterostilbene | [CAS]
475231-21-1 | [Synonyms]
3'-Hydroxypterostilbene
3'-H518-82-1ydroxypterostilbene
4-[2-(3,5-dimethoxyphenyl)ethenyl]benzene-1,2-diol
4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]benzene-1,2-diol
4-[(1E)-2-(3,5-Dimethoxyphenyl)vinyl]benzene-1,2-diol
4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]benzene-1,2-diol
1,2-Benzenediol,4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- | [EINECS(EC#)]
610-361-1 | [Molecular Formula]
C16H16O4 | [MOL File]
475231-21-1.mol | [Molecular Weight]
272.3 |
| Chemical Properties | Back Directory | [Melting point ]
112-115 °C | [Boiling point ]
469.7±45.0 °C(Predicted) | [density ]
1.251±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.51±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Uses]
(E)?-?4-?(3,?5-?Dimethoxystyryl)?benzene-?1,?2-?diol can be used in biological study of evaluation of 90 day repeated dose oral toxicity and reproductive?/developmental toxicity of 3''-?hydroxypterostilbene in experimental animals. | [in vivo]
3'-Hydroxypterostilbene (10 mg/kg; i.p. once per day for 15 days) strongly inhibits tumor growth in vivo[1]. | Animal Model: | 3-4 week old BALB/c nude mice with human colorectal carcinoma COLO 205 tumor xenografts[1] | | Dosage: | 10 mg/kg | | Administration: | Intraperitoneal injection; 10 mg/kg once per day for 15 days | | Result: | Significantly inhibited tumor volume and tumor weight after 15 days treatment compared with the pterostilbene-treated mice, and decreased the protein levels of COX-2, MMP-9, VEGF, cyclin D1 and pro-caspase-3 in mice.
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| [storage]
4°C, protect from light |
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