| Identification | Back Directory | [Name]
4,7-Benzothiazoledione, 5-[[2-(dimethylamino)ethyl]amino]-2-methyl- | [CAS]
477603-18-2 | [Synonyms]
BN82685
BN-82685
BN 82685
BN-82685 (Synonyms: IRC-083065)
4,7-Benzothiazoledione, 5-[[2-(dimethylamino)ethyl]amino]-2-methyl- | [Molecular Formula]
C12H15N3O2S | [MDL Number]
MFCD11840580 | [MOL File]
477603-18-2.mol | [Molecular Weight]
265.33 |
| Chemical Properties | Back Directory | [Melting point ]
142-143 °C | [Boiling point ]
420.4±45.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
8.97±0.28(Predicted) | [color ]
Brown to red |
| Hazard Information | Back Directory | [Uses]
BN-82685 is a a quinone-based CDC25 inhibitor with IC50 of 201 nM, 117 nM, 109 nM, 160 nM, 249 nM, for CDC25C, CDC25C-cat, CDC25A, CDC25B2, CDC25B3, respectively. BN-82685 plays an important role in cancer research[1]. | [References]
[1] Marie-Christine Brezak, et al. IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells. Int J Cancer. 2009 Mar 15;124(6):1449-56. DOI:10.1002/ijc.24080 |
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