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477775-57-8

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477775-57-8 Structure

477775-57-8 Structure
IdentificationBack Directory
[Name]

m-PEG7-Ms
[CAS]

477775-57-8
[Synonyms]

m-PEG8-Ms
m-PEG7-Ms
20-methoxy-1-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane
[Molecular Formula]

C16H34O10S
[MDL Number]

MFCD29060063
[MOL File]

477775-57-8.mol
[Molecular Weight]

418.5
Chemical PropertiesBack Directory
[Boiling point ]

507.4±50.0 °C(Predicted)
[density ]

1.147±0.06 g/cm3(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H413-H317-H315
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
[REACH Registrations]

Active
Hazard InformationBack Directory
[Description]

m-PEG8-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

m-PEG7-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Cleavable Linker; PEGs
[References]

[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.
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