| Identification | Back Directory | [Name]
9,10-Anthracenedione, 1,3-dihydroxy-6-(hydroxymethyl)-8-methoxy- | [CAS]
478-35-3 | [Synonyms]
Carviolin
Carviolin >=95% (LC/MS-UV)
9,10-Anthracenedione, 1,3-dihydroxy-6-(hydroxymethyl)-8-methoxy- | [Molecular Formula]
C16H12O6 | [MDL Number]
MFCD27968017 | [MOL File]
478-35-3.mol | [Molecular Weight]
300.26 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble | [form ]
A solid | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChI]
1S/C16H12O6/c1-22-12-3-7(6-17)2-9-14(12)16(21)13-10(15(9)20)4-8(18)5-11(13)19/h2-5,17-19H,6H2,1H3 | [InChIKey]
XNMZBRJAWRIJII-UHFFFAOYSA-N | [SMILES]
O=C(C1=C(C=C(C=C1C2=O)O)O)C3=C2C=C(C=C3OC)CO |
| Hazard Information | Back Directory | [Description]
Carviolin is an anthraquinone fungal metabolite that has been found in Z. longicaudata with immunosuppressive and antitrypanosomal activities. It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes (IC50s = 4 and 4.5 μg/ml, respectively). Carviolin is active against T. b. brucei (MIC = 41.66 μM). | [Uses]
Carviolin is a compound isolated from the mycelia of the ascomycete Neobulgaria pura. Carviolin inhibits the formation of appressoria in germinating conidia of Magnaporthe grisea on inductive (hydrophobic) surface. Carviolin exhibits moderate cytotoxic, but no antifungal, antibacterial, or phytotoxic activities[1]. | [storage]
Store at -20°C | [References]
[1] Eilbert F, et al. Neobulgarones A approximately F from cultures of Neobulgaria pura, new inhibitors of appressorium formation of Magnaporthe grisea. J Antibiot (Tokyo). 2000;53(10):1123-1129. DOI:10.7164/antibiotics.53.1123 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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