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478149-53-0

478149-53-0 Structure

478149-53-0 Structure
IdentificationBack Directory
[Name]

N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3- c]pyridine- 5-carboxamide hydrochloride PHA 543613 hydrochloride
[CAS]

478149-53-0
[Synonyms]

PHA-543613
PHA-543613 >=98% (HPLC)
PHA 543613 hydrochloride
PHA-543,613 - CAS 478149-53-0 - Calbiochem
(R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxaMide
N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide
Furo[2,3-c]pyridine-5-carboxamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-
N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxaMide hydrochlorid
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxamidehydrochloride
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3- c]pyridine- 5-carboxamide hydrochloride PHA 543613 hydrochloride
[Molecular Formula]

C15H17N3O2
[MDL Number]

MFCD12828748
[MOL File]

478149-53-0.mol
[Molecular Weight]

271.31
Chemical PropertiesBack Directory
[Melting point ]

313-315 °C
[Boiling point ]

508.0±40.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

Store at +4°C
[solubility ]

DMSO: ≥20mg/mL
[form ]

White powder
[pka]

12.19±0.20(Predicted)
[color ]

white to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P
[WGK Germany ]

1
Hazard InformationBack Directory
[Uses]

PHA-543613 has been used to study its effect on recognition memory and neurovascular coupling (NVC) response in β-amyloid (Aβ) 25-35-treated mice. It has also been used to study its effect on Aβ25-35-induced receptor alteration and cognitive impairment in mice.
[Definition]

ChEBI: Pha-543613 is a phosphoramide and an organothiophosphorus compound.
[Biological Activity]

Primary Target
α7 nAChR
Spectrum DetailBack Directory
[Spectrum Detail]

N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3- c]pyridine- 5-carboxamide hydrochloride PHA 543613 hydrochloride(478149-53-0)1HNMR
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