| Identification | Back Directory | [Name]
2-chlorobenzyl 5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl sulfide | [CAS]
478482-74-5 | [Synonyms]
WAY-352753
2-((2-Chlorobenzyl)thio)-5-(pyridin-4-yl)-1,3,4-oxadiazole
2-chlorobenzyl 5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl sulfide
Pyridine, 4-[5-[[(2-chlorophenyl)methyl]thio]-1,3,4-oxadiazol-2-yl]-
synthase,GSK-3,inhibit,WAY 352753,Glycogen synthase kinase 3,WAY352753,Glycogen synthase kinase-3,Inhibitor,Diabetes,glycogen | [Molecular Formula]
C14H10ClN3OS | [MOL File]
478482-74-5.mol | [Molecular Weight]
303.77 |
| Chemical Properties | Back Directory | [Boiling point ]
492.2±55.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (329.20 mM; ultrasonic and warming and heat to 52°C) | [form ]
Solid | [pka]
0.96±0.10(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
GSK3-IN-1 (compound 11) is a GSK-3 inhibitor with an IC50 value of 12 μM. GSK3-IN-1 can be used in the research of diabetes[1]. | [References]
[1] Lars Naerum, et al. Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1525-8. DOI:10.1016/s0960-894x(02)00169-5 |
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