| Identification | Back Directory | [Name]
Eleutherol | [CAS]
480-00-2 | [Synonyms]
Eleutherol
(R)-4-Hydroxy-5-methoxy-3-methylnaphtho[2,3-c]furan-1(3H)-one
Naphtho[2,3-c]furan-1(3H)-one, 4-hydroxy-5-methoxy-3-methyl-, (3R)- | [Molecular Formula]
C14H12O4 | [MDL Number]
MFCD01712360 | [MOL File]
480-00-2.mol | [Molecular Weight]
244.24 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from shallots. | [Uses]
Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 μg/mL and 250 μg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2]. | [Definition]
ChEBI: Eleutherol is a naphthofuran. | [References]
[1] Adriana Campos, et al. Antifungal Activity of Pyranonaphthoquinones Obtained from Cipura paludosa Bulbs. Nat Prod Commun. 2015 Sep;10(9):1589-92. PMID:26594766
[2] Tomohiro Ieyama,et al.α-Glucosidase inhibitors from the bulb of Eleutherine americana. Food Chem.2011 Sep 15;128(2):308-11. DOI:10.1016/j.foodchem.2011.03.021 |
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