Identification | Back Directory | [Name]
Eugenitin | [CAS]
480-12-6 | [Synonyms]
Eugenitin EUGENITIN(RG) 5-hydroxy-7-methoxy-2,6-dimethylchromen-4-one 2,6-Dimethyl-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one 5-Hydroxy-7-methoxy-2,6-dimethyl-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 5-hydroxy-7-methoxy-2,6-dimethyl- | [Molecular Formula]
C12H12O4 | [MOL File]
480-12-6.mol | [Molecular Weight]
220.22 |
Chemical Properties | Back Directory | [Melting point ]
162℃ | [Boiling point ]
402.2±45.0 °C(Predicted) | [density ]
1.267±0.06 g/cm3(Predicted) | [pka]
6.74±0.40(Predicted) | [LogP]
2.878 (est) |
Hazard Information | Back Directory | [Uses]
Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines[1]. | [Definition]
ChEBI: A natural product found in Cyperus teneriffae. | [References]
[1] Andrioli W J, et al. Mycoleptones A–C and polyketides from the endophyte Mycoleptodiscus indicus[J]. Journal of Natural Products, 2014, 77(1): 70-78. DOI:10.1021/np4006822 |
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