| Identification | Back Directory | [Name]
OSAJIN | [CAS]
482-53-1 | [Synonyms]
OSAJIN
NSC 21565
CID 95168
OSAJIN(RG)
Osajin >=95% (LC/MS-ELSD)
5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one
5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-pyrano[2,3-f]chromen-4-one
5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one,5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)- | [Molecular Formula]
C25H24O5 | [MDL Number]
MFCD00076045 | [MOL File]
482-53-1.mol | [Molecular Weight]
404.46 |
| Chemical Properties | Back Directory | [Melting point ]
189° (uncorr), 193° (corr) | [Boiling point ]
632.3±55.0 °C(Predicted) | [density ]
1.258±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
7.00±0.40(Predicted) | [color ]
Yellow | [Cosmetics Ingredients Functions]
ANTIOXIDANT |
| Hazard Information | Back Directory | [Uses]
Osajin is an inhibitor of carbonic anhydrase I and II isoenzymes for therapeutic application such as the treatment of glaucoma. | [Definition]
ChEBI: Osajin is a member of isoflavanones. | [in vivo]
Osajin and pomiferin attenuates the myocardial dysfunction provoked by ischemia reperfusion. This is confirmed by an increase in both antioxidant enzyme values and total antioxidant activity. The cardioprotection provided by osajin and pomiferin treatment results from the suppression of oxidative stress and this correlates with improved ventricular function[3]. | [target]
P450 (e.g. CYP17) | Bcl-2/Bax | Caspase | [storage]
Store at -20°C |
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