| Identification | Back Directory | [Name]
Methanone, (4-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]- | [CAS]
486427-18-3 | [Synonyms]
NMDA receptor potentiator-1
Methanone, (4-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]- | [Molecular Formula]
C26H26ClNO5 | [MOL File]
486427-18-3.mol | [Molecular Weight]
467.94 |
| Hazard Information | Back Directory | [Uses]
NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively[1]. | [IC 50]
NR2C: 4 μM (IC50); NR2D: 5 μM (IC50) | [References]
[1] Stephen F. Traynelis, et al. Subunit selective NMDA receptor potentiators for the treatment of neurological conditions. Patent US8822462. |
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