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489413-54-9

489413-54-9 Structure

489413-54-9 Structure
IdentificationBack Directory
[Name]

[5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone
[CAS]

489413-54-9
[Synonyms]

WAY-272160
[5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone
Methanone, [3-(4-chlorophenyl)-5-(2-furanyl)-4,5-dihydro-1H-pyrazol-1-yl]-2-furanyl-
(3-(4-Chlorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
[Molecular Formula]

C18H13ClN2O3
[MOL File]

489413-54-9.mol
[Molecular Weight]

340.76
Hazard InformationBack Directory
[Uses]

Topoisomerase I/II inhibitor 7 (Compound 5h) is a Topoisomerase I/II inhibitor[1].
[IC 50]

Topoisomerase I; Topoisomerase II
[References]

[1] Ahmad P, et al. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure–activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor[J]. Bioorganic & Medicinal Chemistry, 2016, 24(8): 1898-1908. DOI:10.1016/j.bmc.2016.03.017
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