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492-08-0

492-08-0 Structure

492-08-0 Structure
IdentificationBack Directory
[Name]

PACHYCARPINE
[CAS]

492-08-0
[Synonyms]

D-spartine
d-Sparteine
PACHYCARPINE
Sparteine d-isomer
PACHYCARPINE USP/EP/BP
(+)-Sparteine, 98%, from Parochetus communis D. Don
(1R,2S,9R,10R)-7,15-Diazatetracyclo[7.7.1.02,7.010,15]heptadecane
(7R,7aR,14R,14aS)-Dodecahydro-2H,6H-7,14-methanodipyrido[1,2-a:1',2'-e][1,5]diazocine
(7R,7aR,14R,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7R,7aR,14R,14aS)-
(7R)-1,3,4,7,7aβ,8,9,10,11,13,14,14aα-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
[EINECS(EC#)]

805-899-0
[Molecular Formula]

C15H26N2
[MDL Number]

MFCD00869353
[MOL File]

492-08-0.mol
[Molecular Weight]

234.38
Chemical PropertiesBack Directory
[Melting point ]

201℃
[Boiling point ]

174°C/8mmHg(lit.)
[density ]

1.08
[refractive index ]

n/D1.527
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[solubility ]

Chloroform (slightly), Ethanol
[form ]

liquid
[pka]

10.08±0.20(Predicted)
[color ]

Colourless to Light Yellow
[λmax]

202nm(CH3CN)(lit.)
[InChI]

InChI=1S/C15H26N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h12-15H,1-11H2/t12-,13-,14-,15+/m1/s1
[InChIKey]

SLRCCWJSBJZJBV-TUVASFSCSA-N
[SMILES]

N12CCCC[C@@]1([H])[C@]1([H])C[C@]([H])(C2)[C@@]2([H])CCCCN2C1
[CAS DataBase Reference]

492-08-0
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332
[Precautionary statements ]

P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
[RTECS ]

RT0620000
[HS Code ]

2933998090
[Toxicity]

LD50 scu-mus: 90 mg/kg FATOAO 21(5),46,58
Hazard InformationBack Directory
[Uses]

(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.
[Safety Profile]

Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
[storage]

Store at -20°C, protect from light
[References]

[1] Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5. PMID:1715014
Spectrum DetailBack Directory
[Spectrum Detail]

PACHYCARPINE(492-08-0)MS
PACHYCARPINE(492-08-0)1HNMR
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