| Identification | Back Directory | [Name]
N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide] | [CAS]
494830-67-0 | [Synonyms]
N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide]
N,N'-ethane-1,2-diylbis[2-(4-tert-butylphenoxy)acetamide]
Acetamide, N,N'-1,2-ethanediylbis[2-[4-(1,1-dimethylethyl)phenoxy]- | [Molecular Formula]
C26H36N2O4 | [MDL Number]
MFCD03542891 | [MOL File]
494830-67-0.mol | [Molecular Weight]
440.58 |
| Hazard Information | Back Directory | [Uses]
NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity[1]. | [storage]
Store at -20°C | [References]
[1] Wang X, et al. Identification of a small-molecule compound that inhibits homodimerization of oncogenic NAC1 protein and sensitizes cancer cells to anticancer agents. J Biol Chem. 2019 May 17. pii: jbc.RA119.007664. DOI:10.1074/jbc.RA119.007664 |
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