| Identification | Back Directory | [Name]
Lypressin | [CAS]
50-57-7 | [Synonyms]
LVP
diapid
postacton
LYPRESSIN
LYSPRESSIN
Lysipressin
Vasopressin
syntopressin
CYFQNCPKG-NH2
lysinepitressin
LyspessinAcetate
Lypressin Acetate
8-Lys-Vasopressin
LYSINE VASOPRESSIN
[LYS8]-VASOPRESSIN
Lysipressin Acetate
l-lysinevasopressin
vasopressin 8-lysine
(8-lysine)vasopressin
8-l-lysine-vasopressi
8-l-lysinevasopressin
Vasopressin,8-L-lysine-
Lysine vasopressin, Lyspressin
Terlipressin (4-12), Lypressin, LVP
CYS-TYR-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2
H-CYS-TYR-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2
c[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2
H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Cys1-Cys6)
H-CYS-TYR-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2, CYS1,6, CYCLIC
H-CYS-TYR-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2, (DISULFIDE BOND)
L-Cys(1)-L-Tyr-L-Phe-L-Gln-L-Asn-L-Cys(1)-L-Pro-L-Lys-Gly-NH2
L-Cys(1)-L-Tyr-L-Phe-L-Glu(NH2)-L-Asp(NH2)-L-Cys(1)-L-Pro-L-Lys-Gly-NH2 | [EINECS(EC#)]
200-050-5 | [Molecular Formula]
C46H65N13O12S2 | [MDL Number]
MFCD00076754 | [MOL File]
50-57-7.mol | [Molecular Weight]
1056.22 |
| Chemical Properties | Back Directory | [Boiling point ]
1610.4±65.0 °C(Predicted) | [density ]
1.1080 (rough estimate) | [refractive index ]
1.6700 (estimate) | [storage temp. ]
−20°C
| [form ]
Solid | [pka]
9.90±0.15(Predicted) | [color ]
White to off-white | [Sequence]
H-[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2，(Disulfide bridge: Cys-Cys) | [Major Application]
USP Biologics
pharmaceutical (small molecule) | [InChIKey]
NKWAIKZITYLOMT-DHSVNZEYSA-N | [SMILES]
C1(N)CSSCC(C(=O)N2C(C(=O)CC(CCCCN)C(=O)NCC(=O)N)CCC2)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC2C=CC(O)=CC=2)NC1=O)CCC(=O)N |
| Hazard Information | Back Directory | [Uses]
Hormone (antidiuretic). | [Definition]
ChEBI: (2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloeicos-4-yl]-oxomethyl]-2-pyrrolidinecarboxamide is a cyclic peptide. | [Brand name]
Pitressin
(Parke-Davis). | [General Description]
Lypressin is synthetic 8-L-lysine vasopressin,a polypeptide similar to ADH. The lysine analog isconsidered more stable, and it is absorbed rapidly from thenasal mucosa. Lypressin (Diapid) is pharmaceutically availableas a topical solution, spray, 50 pressor units(185 g)/mL in 5-mL containers. Usual dosage, topical (intranasal),one or more sprays applied to one or both nostrilsone or more times daily. |
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