| Identification | Back Directory | [Name]
DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(RG) | [CAS]
501938-01-8 | [Synonyms]
DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(RG)
β-D-Xylopyranoside, (3β,12β,16β,23R,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl | [Molecular Formula]
C37H56O10 | [MDL Number]
MFCD07783721 | [MOL File]
501938-01-8.mol | [Molecular Weight]
660.85 |
| Hazard Information | Back Directory | [Uses]
pharmaceutical | [Definition]
ChEBI: 23-epi-26-deoxyactein is a triterpenoid. It has a role as a metabolite. | [in vivo]
23-epi-26-Deoxyactein (DA: 5 and 10 mg/kg/d) significantly lowers body weight gain, fat mass, and liver weight in HFD-fed mice. 23-epi-26-Deoxyactein (DA) also reduces insulin resistance and serum lipoprotein levels in HFD-fed mice[1].
23-epi-26-Deoxyactein (DA) promotes adipocyte lipolysis in mice through activating the AMPK signaling and SIRT1-FOXO1 pathway[1].
| Animal Model: | Diet induced obesity in C57BL/6 mice[1]. | | Dosage: | 1-10 mg/kg. | | Administration: | Orally, daily for 12 weeks. | | Result: | Lowered body weight gain, fat mass, and liver weight.
5 mg/kg/d DA significantly improved HFD-induced glucose intolerance.
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
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| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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