ChemicalBook--->CAS DataBase List--->501948-05-6

501948-05-6

501948-05-6 Structure

501948-05-6 Structure
IdentificationBack Directory
[Name]

3-[(4-Cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-alpha-oxo-1-indolizineacetamide
[CAS]

501948-05-6
[Synonyms]

STA 5312
Rosabulin
3-[(4-cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-α-oxo-1-indolizineacetamide
1-Indolizineacetamide, 3-[(4-cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-α-oxo-
3-[(4-Cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-alpha-oxo-1-indolizineacetamide
[Molecular Formula]

C22H16N4O2S
[MDL Number]

MFCD13152388
[MOL File]

501948-05-6.mol
[Molecular Weight]

400.45
Chemical PropertiesBack Directory
[Melting point ]

233 ºC
[density ]

1.34
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

8.00±0.46(Predicted)
[color ]

Light yellow to green yellow
Hazard InformationBack Directory
[Uses]

Treatment of therapeutic resistant cancers.
[in vivo]

When dosed orally or intravenously, Rosabulin (STA 5312) has shown in vivo activity in several murine tumors as well as human tumor xenograft models, including drug resistant tumors[1].

[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

3-[(4-Cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-alpha-oxo-1-indolizineacetamide(501948-05-6)1HNMR
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