| Identification | Back Directory | [Name]
Sortin1 | [CAS]
503837-98-7 | [Synonyms]
Sortin1
CS-2132
1H-Indeno[1,2-b]pyridine-3-carboxylic acid, 4-[5-(4-carboxyphenyl)-2-furanyl]-4,5-dihydro-2-methyl-5-oxo-, 3-methyl ester | [Molecular Formula]
C26H19NO6 | [MDL Number]
MFCD02217969 | [MOL File]
503837-98-7.mol | [Molecular Weight]
441.43 |
| Chemical Properties | Back Directory | [Boiling point ]
675.4±55.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (226.54 mM) | [form ]
Solid | [pka]
4.18±0.10(Predicted) | [color ]
Pink to red |
| Hazard Information | Back Directory | [Uses]
Sortin1 is a vacuolar protein sorting inhibitor that targets carboxypeptidase Y (CPY). Sortin1 is a soluble and membrane vacuolar marker molecule in plants and yeast[1]. | [References]
[1] Vásquez-Soto B, et al. Sortin2 enhances endocytic trafficking towards the vacuole in Saccharomyces cerevisiae. Biol Res. 2015 Jul 25;48(1):39. DOI:10.1186/s40659-015-0032-9
[2] Zouhar J, et al. Sorting inhibitors (Sortins): Chemical compounds to study vacuolar sorting in Arabidopsis. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9497-501. DOI:10.1073/pnas.0402121101
[3] Rosado A, et al. Sortin1-hypersensitive mutants link vacuolar-trafficking defects and flavonoid metabolism in Arabidopsis vegetative tissues. Chem Biol. 2011 Feb 25;18(2):187-97. DOI:10.1016/j.chembiol.2010.11.015
[4] Orr DJ, et al. 1H NMR-based metabolomics methods for chemical genomics experiments. Methods Mol Biol. 2014;1056:225-39. DOI:10.1007/978-1-62703-592-7_21 |
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Cckinase, Inc.
|
| Tel: |
+1 (732)236-3202 |
| Website: |
www.cckinase.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|