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50686-98-1

50686-98-1 Structure

50686-98-1 Structure
IdentificationBack Directory
[Name]

15-Aza-24-methylene-D-homocholestadiene
[CAS]

50686-98-1
[Synonyms]

A25822B
A-25822
Azasterol
15-Azasterol
Antibiotic A-25822B
15-Aza-24-methylene-D-homocholestadiene
15-Aza-D-homo-5α-ergosta-8,14,24(28)-trien-3β-ol
Naphtho[1,2-h]quinolin-8-ol, 1-[(1R)-1,5-dimethyl-4-methylenehexyl]-1,2,3,5,6,6a,7,8,9,10,10a,11,12,12a-tetradecahydro-10a,12a-dimethyl-, (1R,6aS,8S,10aS,12aR)-
[Molecular Formula]

C28H45NO
[MDL Number]

MFCD32012258
[MOL File]

50686-98-1.mol
[Molecular Weight]

411.66
Chemical PropertiesBack Directory
[Boiling point ]

513.1±50.0 °C(Predicted)
[density ]

1.09±0.1 g/cm3(Predicted)
[pka]

15.05±0.70(Predicted)
Hazard InformationBack Directory
[Description]

A25822B is an antifungal agent. It is an azasterol that may decrease the ratio of unsaturated to saturated fatty acids.
[Uses]

A25822B is an antifungal agent, with a MIC of 1 μM for Ascosphaera apis. A25822B causes conformational changes in mitochondria and disruption of spore membrane structure. A25822B can be used for the research of bee chalk disease[1].
[References]

[1] Liu TP, et al. In vitro activity of 15-azasterol (A25822B) against chalkbrood pathogen Ascosphaera apis in the honey bee[J]. Mycopathologia, 1991, 115: 175-184.
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