Identification | Back Directory | [Name]
15-Aza-24-methylene-D-homocholestadiene | [CAS]
50686-98-1 | [Synonyms]
A25822B A-25822 Azasterol 15-Azasterol Antibiotic A-25822B 15-Aza-24-methylene-D-homocholestadiene 15-Aza-D-homo-5α-ergosta-8,14,24(28)-trien-3β-ol Naphtho[1,2-h]quinolin-8-ol, 1-[(1R)-1,5-dimethyl-4-methylenehexyl]-1,2,3,5,6,6a,7,8,9,10,10a,11,12,12a-tetradecahydro-10a,12a-dimethyl-, (1R,6aS,8S,10aS,12aR)- | [Molecular Formula]
C28H45NO | [MDL Number]
MFCD32012258 | [MOL File]
50686-98-1.mol | [Molecular Weight]
411.66 |
Hazard Information | Back Directory | [Description]
A25822B is an antifungal agent. It is an azasterol that may decrease the ratio of unsaturated to saturated fatty acids. | [Uses]
A25822B is an antifungal agent, with a MIC of 1 μM for Ascosphaera apis. A25822B causes conformational changes in mitochondria and disruption of spore membrane structure. A25822B can be used for the research of bee chalk disease[1]. | [References]
[1] Liu TP, et al. In vitro activity of 15-azasterol (A25822B) against chalkbrood pathogen Ascosphaera apis in the honey bee[J]. Mycopathologia, 1991, 115: 175-184. |
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