| Identification | Back Directory | [Name]
5-methoxy-1h-isoindole-1,3(2h)-dione | [CAS]
50727-04-3 | [Synonyms]
4-MethoxyphthaliMide
5-methoxyisoindole-1,3-dione
5-methoxyisoindoline-1,3-dione
5-methoxy-1h-isoindole-1,3(2h)-dione
1H-Isoindole-1,3(2H)-dione, 5-methoxy- | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C9H7NO3 | [MDL Number]
MFCD13248628 | [MOL File]
50727-04-3.mol | [Molecular Weight]
177.16 |
| Chemical Properties | Back Directory | [Melting point ]
219 °C | [density ]
1.346±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
9.84±0.20(Predicted) | [Appearance]
White to off-white Solid |
| Questions And Answer | Back Directory | [Uses]
5-Methoxyisoindoline-1,3-dione is used as a reagent in the synthesis of KUP-1, a photoreactive and fluorescent pyrethroid, which can be used as a tool for photoaffinity labelling. |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 5-methoxyisoindolane-1,3-dione from 5-methoxy-1-indanone: In a stainless steel autoclave with PTFE lining, 0.01 g of MnO2 catalyst, 0.5 mmol of 5-methoxy-1-indanone, 0.2 g of ammonia (25 wt%) and 2 g of chlorobenzene were added in sequence. The reaction temperature was raised to 110 °C by an automatic temperature controller, followed by the passage of 0.6 MPa oxygen, which was maintained at a constant pressure, and the reaction was continued for 4 hours. Upon completion of the reaction, the reaction mixture was analyzed by GC-MS and the yield of 5-methoxyisoindolidine-1,3-dione was measured to be 85%. | [References]
[1] Patent: CN106278990, 2017, A. Location in patent: Paragraph 0013; 0017; 0018; 0020; 0023; 0028 |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
BePharm Ltd
|
| Tel: |
400-685-9117 |
| Website: |
www.bepharm.com |
|