| Identification | Back Directory | [Name]
L-Glutamine, L-leucyl-L-leucyl-L-α-glutamyl-L-phenylalanyl-L-tyrosyl-L-leucyl-L-alanyl-L-methionyl-L-prolyl-L-phenylalanyl-L-alanyl-L-threonyl-L-prolyl-L-methionyl-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-leucyl-L-alanyl-L-arginyl-L-arginyl-L-seryl-L-leucyl-L-alanyl- | [CAS]
508230-31-7 | [Synonyms]
L-Glutamine, L-leucyl-L-leucyl-L-α-glutamyl-L-phenylalanyl-L-tyrosyl-L-leucyl-L-alanyl-L-methionyl-L-prolyl-L-phenylalanyl-L-alanyl-L-threonyl-L-prolyl-L-methionyl-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-leucyl-L-alanyl-L-arginyl-L-arginyl-L-seryl-L-leucyl-L-alanyl- | [Molecular Formula]
C131H206N32O36S2 | [MDL Number]
MFCD11113693 | [MOL File]
508230-31-7.mol | [Molecular Weight]
2869.4 |
| Chemical Properties | Back Directory | [density ]
1.42±0.1 g/cm3(Predicted) | [Sequence]
Leu-Leu-Glu-Phe-Tyr-Leu-Ala-Met-Pro-Phe-Ala-Thr-Pro-Met-Glu-Ala-Glu-Leu-Ala-Arg-Arg-Ser-Leu-Ala-Gln |
| Hazard Information | Back Directory | [Uses]
NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-type CD4+ T cells when presented in the context of HLA-DR and HLA-DP4 molecules[1]. | [References]
[1] Maja Mandic, et al. One NY-ESO-1-derived epitope that promiscuously binds to multiple HLA-DR and HLA-DP4 molecules and stimulates autologous CD4+ T cells from patients with NY-ESO-1-expressing melanoma. J Immunol. 2005 Feb 1;174(3):1751-9. DOI:10.4049/jimmunol.174.3.1751 |
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