| Identification | Back Directory | [Name]
5'-(N-CYCLOPROPYL)CARBOXAMIDOADENOSINE | [CAS]
50908-62-8 | [Synonyms]
CPCA
NCPCA
n-cyclopropyladenosine-5’-carboxamide
5'-N-Cyclopropylcarboxamide adenosine
5'-(N-CYCLOPROPYL)CARBOXAMIDOADENOSINE
adenosine-5’-(n-cyclopropyl)carboxamide
5'-(N-CYCLOPROPYL)-CARBOXAMIDOADENOSINE POTENT A2 ADENOSINE R
1-(6-amino-9h-purin-9-yl)-n-cyclopropyl-1-deoxy-ribofuranuronamid
1-(6-amino-9h-purin-9-yl)-n-cyclopropyl-1-deoxyribofuranuronamide
1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-β-D-ribofuranuronamide
N-Cyclopropyl-1-(6-amino-9H-purine-9-yl)-1-deoxy-β-D-ribofuranuronamide
β-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-
5'(NCyclopropyl)carboxamidoadenosine,5' (N Cyclopropyl)carboxamidoadenosine
(2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-3,4-dihydroxytetrahydrofuran-2-carboxamide | [Molecular Formula]
C13H16N6O4 | [MDL Number]
MFCD00055130 | [MOL File]
50908-62-8.mol | [Molecular Weight]
320.3 |
| Chemical Properties | Back Directory | [Boiling point ]
459.21°C (rough estimate) | [density ]
1.2633 (rough estimate) | [refractive index ]
1.7000 (estimate) | [storage temp. ]
2-8°C | [solubility ]
DMF: 25 mg/ml; DMSO: 14 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
12.88±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
5''-(N-Cyclopropyl)carboxamidoadenosine is a specific adenosine A2 receptor agonist with antipyretic and anticonvulsant activity. It stimulates the production of cyclic AMP in CHO-K1 cells with an EC50 value of 5.3 μM. | [Uses]
5'-(N-Cyclopropyl)carboxamidoadenosine (CPCA) is an adenosine A2 receptor agonist[1]. | [storage]
Store at -20°C | [References]
[1] J Malhotra, et al. Effect of adenosine receptor modulation on pentylenetetrazole-induced seizures in rats. Br J Pharmacol. 1997 Jan;120(2):282-8. DOI:10.1038/sj.bjp.0700869 |
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