| Identification | Back Directory | [Name]
2',3'-dideoxy-3'-fluorocytidine | [CAS]
51246-79-8 | [Synonyms]
Fddcyd
3'-Fddc
Aids000014
Aids-000014
3'-Fluoro-2',3'-dideoxycytidine
2',3'-dideoxy-3'-fluorocytidine
2',3'-Dideoxy-3'-fluorocytidine
Cytidine, 2',3'-dideoxy-3'-fluoro-
2’,3’-Dideoxy-3’-fluorocytidine, FddC
2’,3’-Dideoxy-3’-fluorocytidine, FddC, HIV-1 inhibitor
1-(3-fluoro-2,3-dideoxy-β-D-erythro-pentofuranosyl)cytosine | [Molecular Formula]
C9H12FN3O3 | [MOL File]
51246-79-8.mol | [Molecular Weight]
229.21 |
| Chemical Properties | Back Directory | [Boiling point ]
418.0±55.0 °C(Predicted) | [density ]
1.67±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
14.44±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
2’,3’-Dideoxy-3’-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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