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51533-70-1

51533-70-1 Structure

51533-70-1 Structure
IdentificationBack Directory
[Name]

DIETHYL (2-METHYLALLYL)PHOSPHONATE 97
[CAS]

51533-70-1
[Synonyms]

Diethyl (2-methylallyl)phosphonate 97%
DIETHYL (2-METHYLALLYL)PHOSPHONATE 97
3-diethoxyphosphoryl-2-methylprop-1-ene
Diethyl P-(2-methyl-2-propen-1-yl)phosphonate
Phosphonic acid, P-(2-methyl-2-propen-1-yl)-, diethyl ester
[Molecular Formula]

C8H17O3P
[MDL Number]

MFCD05664300
[MOL File]

51533-70-1.mol
[Molecular Weight]

192.19
Chemical PropertiesBack Directory
[Boiling point ]

62 °C/0.1 mmHg (lit.)
[density ]

1.013 g/mL at 25 °C (lit.)
[refractive index ]

n20/D 1.4380(lit.)
[Fp ]

>230 °F
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36
[Safety Statements ]

26
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Diethyl (2-methylallyl)phosphonate can be used as a reagent in the Horner-Wadsworth-Emmons reaction to form conjugated carbon–carbon double bonds.
It can also be used as a reactant for:
  • Enantioselective total synthesis of 10-isocyano-4-cadinene as antifouling agent.
  • Regiospecific preparation of 4-oxo-2-alkenylphosphonates (OAP) via silylation followed by Friedel-Crafts acylation and isomerization. OAP can serve as building blocks for the construction of polyethylenic chains.
  • The synthesis of azaphosphone as a potent analgesic/anti-inflammatory agents.

[General Description]

Diethyl (2-methylallyl)phosphonate is an organophosphorous compound. It participates in the synthesis of α-aminophosphonate derivatives and azaphosphones. The analgesic/antiinflammatory properties of these derivatives were evaluated.
[reaction suitability]

reaction type: C-C Bond Formation
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