| Identification | Back Directory | [Name]
3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)- | [CAS]
51557-10-9 | [Synonyms]
(E)-4-(Naphthalen-2-yl)but-3-en-2-one
3-Buten-2-one, 4-(2-naphthalenyl)-, (3E)- | [Molecular Formula]
C14H12O | [MOL File]
51557-10-9.mol | [Molecular Weight]
196.24 |
| Chemical Properties | Back Directory | [Melting point ]
94-95 °C | [Boiling point ]
370.0±11.0 °C(Predicted) | [density ]
1.101±0.06 g/cm3(Predicted) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(E)-4-(Naphthalen-2-yl)but-3-en-2-one (Compound 7) is a small active molecule that can be used as building block. (E)-4-(Naphthalen-2-yl)but-3-en-2-one exhibits anti-leukemic activity, that inhibits the proliferation of human chronic myeloid leukemia cell K562 with an IC50 of 7.6 μM[1]. | [References]
[1] Ducki S, et al. Synthesis and cell growth inhibitory properties of substituted (E)-1-phenylbut-1-en-3-ones[J]. Bioorganic & Medicinal Chemistry Letters, 1997, 7(24): 3091-3094. |
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