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516-42-7

516-42-7 Structure

516-42-7 Structure
IdentificationBack Directory
[Name]

ALPHA-CORTOLONE
[CAS]

516-42-7
[Synonyms]

CORTOLONE
α-Cortolone
α-Cortolone-d5
ALPHA-CORTOLONE
Alpha Cortolone D5
A-cortolone crystalline
5β-Pregnane-3α,17α,20α,21-tetrol-11-one
5β-Pregnan-3α, 17, 20α, 21-Tetrol-11-One
3α,17α,20α,21-Tetrahydroxy-5β-pregnan-11-one
(20S)-3α,17,20,21-Tetrahydroxy-5β-pregnan-11-one
5-BETA-PREGNAN-3-ALPHA, 17,20-ALPHA, 21-TETROL-11-ONE
5BETA-PREGNAN-3ALPHA,17ALPHA,20ALPHA,21-TETROL-11-ONE
3-ALPHA,17-ALPHA,20-ALPHA,21-TETRAHYDROXY-5-BETA-PREGNAN-11-ONE
(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
[Molecular Formula]

C21H34O5
[MDL Number]

MFCD00056388
[MOL File]

516-42-7.mol
[Molecular Weight]

366.49
Chemical PropertiesBack Directory
[Melting point ]

208-209°
[alpha ]

D25 +44° (c = 0.5 in ethanol); D28 +34.2° (ethanol)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

α-Cortolone is a human urinary metabolite of Cortisol ((H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
[Definition]

ChEBI: Cortolone is a 21-hydroxy steroid.
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