| Identification | Back Directory | [Name]
tipepidine | [CAS]
5169-78-8 | [Synonyms]
At 327
Cr/662
Bitiodin
tipepidine
Brn 0212554
tipepidine USP/EP/BP
14698-07-8 (Citrate[1:1])
3-(Dithien-2-ylmethylene)-1-methylpiperidine
1-Methyl-3-piperidylidenedi(2-thienyl)methane
3-(Di-2-thienylmethylene)-1-methyl-piperidine
Piperidine, 3-(di-2-thienylmethylene)-1-methyl-
3-(dithiophen-2-ylmethylidene)-1-methylpiperidine
3-( di-2-thienylmethylene)-1-methylpiperidine hydrochloride | [Molecular Formula]
C15H17NS2 | [MDL Number]
MFCD00552099 | [MOL File]
5169-78-8.mol | [Molecular Weight]
275.43 |
| Chemical Properties | Back Directory | [Melting point ]
64-65° | [Boiling point ]
bp4-5 178-184° | [density ]
1.1947 (rough estimate) | [refractive index ]
1.5300 (estimate) | [form ]
Solid | [pka]
8.23±0.20(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Originator]
Sotal,G. Ramon | [Definition]
ChEBI: Tipepidine is a member of piperidines. | [Manufacturing Process]
From ethyl 1-methylpiperidine-3-carboxylate (which was prepared by
hydrogenation of ethyl nicotinate with Ni-catalyst and then by methylation by
action dimethyl sulfate) and 2-thienyl magnesium bromide was synthesized
1,1-di(thiophen-2-yl)-2-(3'-N-methylpiperidine), 3-(di-2-thienylmethylene)-1-
methylpiperidine was obtained by dehydration of 1,1-di(thiophen-2-yl)-2-(3'-
N-methylpiperidine) by action of base. | [Therapeutic Function]
Antitussive, Expectorant |
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