| Identification | Back Directory | [Name]
N-T-BOC-PYRROLE | [CAS]
5176-27-2 | [Synonyms]
e-1-CarboxyL
ate(WX690266)
N-Boc-Pyrrole
1-Boc-pyrrole
N-T-BOC-PYRROLE
N-BOC-1H-PYRROLE
N-T-BOC-PYRROLE-1
N-Boc-pyrrole 98%
N-Boc-pyrrole
N-(t-Butoxycarbonyl)pyrrole
tert-butyl-pyrrole-carboxylate
TERT-BUTYL PYRROL-1-CARBOXYLATE
TERT-BUTYL 1-PYRROLECARBOXYLATE
tert-Butylpyrrole-1-carboxylate
N-tert-Butoxycarbonyl-1H-pyrrol
t-Butyl 1H-pyrrole-1-carboxylate
N-tert-Butoxycarbonyl-1H-pyrrole
N-(tert-butyloxycarbonyl)pyrrole
N-Boc-pyrrole, 97%, for synthesis
tert-butyl-pyrrole-carboxylate,98%
tert-butyl 1H-pyrrole-1-carboxylate
1-pyrrolecarboxylic acid tert-butyl ester
Pyrrole-1-carboxylic Acid tert-Butyl Ester
Tert-Butyl 1H-Pyrrole-1-Carboxylate(WX690266)
N-Boc-pyrrole,tert-Butyl 1-pyrrolecarboxylate
1H-Pyrrole-1-carboxylic acid, 1,1-diMethylethyl ester | [Molecular Formula]
C9H13NO2 | [MDL Number]
MFCD00209559 | [MOL File]
5176-27-2.mol | [Molecular Weight]
167.21 |
| Chemical Properties | Back Directory | [Boiling point ]
91-92 °C20 mm Hg(lit.)
| [density ]
1 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.4685(lit.)
| [Fp ]
167 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Acetonitrile, Dichloromethane, Ethyl Acetate, Methanol, Tetrahydrofuran | [form ]
Solution | [pka]
-6.10±0.70(Predicted) | [color ]
Colorless to yellow | [InChIKey]
IZPYBIJFRFWRPR-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless liquid | [Uses]
N-Boc-pyrrole was used in the synthesis of 1-(tert-butoxycarbonyl)-1H-pyrrol-2-ylboronic acid by treating with n-BuLi and subsequent reaction with trimethyl borate.
It may be used as starting material in the synthesis of the following:
- tropane drivatives
- N-boc-2-(4-methoxyphenyl)pyrrole
- N-boc-pyrrol-2-ylboronic acid
| [Uses]
Pyrrole-1-carboxylic Acid tert-Butyl Ester is an intermediate in the synthesis of pyrrole derived anti-cancer Agent. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 31, p. 764, 1966 DOI: 10.1021/jo01341a027 | [General Description]
N-Boc-pyrrole is an N-protected pyrrole. It undergoes Diels–Alder reaction with enantiomerically pure allene-1,3-dicarboxylates to form endo-adducts with retention in configurations at two newly generated stereogenic centers. It also undergoes cyclopropanation with methyl phenyldiazoacetate to form both monocyclopropane and dicyclopropane. Its Ir-catalyzed C-H borylation followed by cross coupling with 3-chlorothiophene to form biheterocycle has been reported. |
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