| Identification | Back Directory | [Name]
2-[(3-chlorophenyl)Methyl]-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane | [CAS]
517920-59-1 | [Synonyms]
2-(3-Chlorobenzyl)
(3-CHLOROBENZYL)BORONIC ACID PINACOL ESTER
2-[(3-chlorophenyl)Methyl]-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
1,3,2-Dioxaborolane, 2-[(3-chlorophenyl)methyl]-4,4,5,5-tetramethyl- | [Molecular Formula]
C13H18BClO2 | [MDL Number]
MFCD10698516 | [MOL File]
517920-59-1.mol | [Molecular Weight]
252.54 |
| Chemical Properties | Back Directory | [Boiling point ]
298.8±23.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [Appearance]
Colorless to light yellow Liquid |
| Hazard Information | Back Directory | [Synthesis]
Example 5: Magnesium chips (16.8 mg, 0.7 mmol) were added to the reaction system as an activator under argon protection. Catalyst Fe(acac)3 (3.5 mg, 0.010 mmol, 2 mol%), p-chlorobenzyl chloride (157 μl, 1.35 mmol) and bis(pinacolato)borate (127.0 mg, 0.5 mmol) were added sequentially to tetrahydrofuran (1 ml). The reaction was carried out at -10 °C for 5 h, followed by addition of water to terminate the reaction. The reaction mixture was extracted with ethyl acetate and the product was analyzed by gas chromatography in 81% yield. | [References]
[1] Chemistry Letters, 2002, # 8, p. 780 - 781
[2] Patent: CN107903281, 2018, A. Location in patent: Paragraph 0026
[3] Journal of the American Chemical Society, 2012, vol. 134, # 25, p. 10693 - 10697
[4] Journal of the American Chemical Society, 2014, vol. 136, # 27, p. 9521 - 9523
[5] Chemistry Letters, 2002, # 8, p. 780 - 781 |
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