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518-11-6

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518-11-6 Structure

518-11-6 Structure
IdentificationBack Directory
[Name]

DEMECOLCEINE
[CAS]

518-11-6
[Synonyms]

NSC 36559
DEMECOLCEINE
N-DESACETYL-N-METHYLCOLCHICEINE
7-DeacetaMido-7-(MethylaMino)colchiceine
(7S)-6,7-Dihydro-10-hydroxy-1,2,3-triMethoxy-7-(MethylaMino)-benzo[a]heptalen-9(5H)-one
[Molecular Formula]

C20H23NO5
[MDL Number]

MFCD01736982
[MOL File]

518-11-6.mol
[Molecular Weight]

357.4
Chemical PropertiesBack Directory
[Appearance]

Yellow Solid
[Melting point ]

120-122°C
[storage temp. ]

-20?C Freezer
Hazard InformationBack Directory
[Chemical Properties]

Yellow Solid
[Uses]

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
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