| Identification | Back Directory | [Name]
IsoMaculosidine | [CAS]
518-96-7 | [Synonyms]
IsoMaculosidine
6,8-dimethoxy-9-methylfuro[2,3-b]quinolin-4-one
Furo[2,3-b]quinolin-4(9H)-one, 6,8-dimethoxy-9-methyl- | [Molecular Formula]
C14H13NO4 | [MDL Number]
MFCD28100654 | [MOL File]
518-96-7.mol | [Molecular Weight]
259.26 |
| Chemical Properties | Back Directory | [Melting point ]
168-170℃ | [Boiling point ]
434.3±45.0 °C(Predicted) | [density ]
1.268±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
1.65±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
This alkaloid is very hygroscopic and difficult to obtain crystalline. It occurs in
the roots of Dictamnus albus and is somewhat unstable, turning red on exposure
to light. Isolation under mild conditions show it to be a true alkaloid and not an
artifact. | [Uses]
Isomaculosidine is an alkaloid that can be isolated from D. dasycarpus. Isomaculosidine can inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 microglial cells[1]. | [References]
Gellert et al., Herba Hung., 10, 123 (1971)
Storer, Young., Tetrahedron, 29, 1217 (1973) |
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