| Identification | Back Directory | [Name]
D(-)-AMETHOPTERIN | [CAS]
51865-79-3 | [Synonyms]
6-MTX(D)
d-methotrexate
R-Methotrexate
Einecs 257-482-2
D(-)-AMETHOPTERIN
D-(-)-AMETHOPTERIN HYDRATE
Methotrexate Impurity 6(EP-F)
(-) - AMETHOPTERIN - D - METHOTREXATE
D(-)-4-AMINO-N10-METHYLPTEROYLGLUTAMIC ACID
Methotrexate Impurity 6（Methotrexate EP Impurity F）
MethotrexateEPImpurityFDisodiumSalt-MethotrexateDisodiumSalt)
D-(-)-N-(2,4-diamino-6-pteridinyl(dimethylamino)benzoyl)glutamic acid
Methotrexate EP Impurity F Disodium Salt ((R)-Methotrexate Disodium Salt)
n-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-d-glutamicacid
(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-D-glutamic acid
N-[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]-D-glutamic acid
D-Glutamic acid, N-(4-(((2,4-diamino-6-pteridyl)methyl)methylamino)benzoyl)-
D-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, D-
D-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI)
R-Methotrexate (5 mg) ((R)-2-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic acid) | [EINECS(EC#)]
257-482-2 | [Molecular Formula]
C20H22N8O5 | [MDL Number]
MFCD00006710 | [MOL File]
51865-79-3.mol | [Molecular Weight]
454.44 |
| Chemical Properties | Back Directory | [Melting point ]
195 °C | [Boiling point ]
561.26°C (rough estimate) | [density ]
1.4080 (rough estimate) | [refractive index ]
1.6910 (estimate) | [storage temp. ]
-20°C | [solubility ]
Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly） | [form ]
Solid | [pka]
3.47±0.10(Predicted) | [color ]
Dark Yellow to Very Dark Yellow | [Stability:]
Hygroscopic | [Major Application]
pharmaceutical (small molecule) | [InChIKey]
FPJYMUQSRFJSEW-UHFFFAOYSA-N | [SMILES]
O.CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O |
| Hazard Information | Back Directory | [Chemical Properties]
Solid | [Uses]
R-Methotrexate is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic. |
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