| Identification | Back Directory | [Name]
1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one | [CAS]
519-98-2 | [Synonyms]
N-Methy
noramidopyrine
Noraminopyrine
Methylaminophenazone
Metamizole Impurity C
Methylaminoantipyrine
N-Methylaminophenazone
4-Methylaminophenazone
Monomethylaminoantipyrine
4-(Methylamino)-antipyrine
4-Monomethylaminophenazone
4-Monomethylaminoantipyrine
4-(N-Methyl)-aminoantipyrine
ANTIPYRINE, 4-(METHYLAMINO)-
MetaMizole IMpurity C (4-MethylaMinoantipyrine)
1,5-dimethyl-4-methylamino-2-phenyl-3-pyrazolone
1,5-dimethyl-4-(methylamino)-2-phenylpyrazol-3-one
1,5-dimethyl-4-(methylamino)-2-phenyl-pyrazol-3-one
2,3-Dimethyl-4-methylamino-1-phenyl-3-pyrazolin-5-one
Metamizole Sodium Impurity 3（Minocycline EP Impurity C）
3H-pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(methylamino)
Metamizole Sodium Impurity 3（Metamizole Sodium EP Impurity C）
1,5-dimethyl-4-(methylamino)-2-phenyl-1,2-dihydropyrazol-3-one
1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one
2-(1-cyclohexa-2,4-dienyl)-1,5-dimethyl-4-(methylamino)-3-pyrazolone
3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-
1,5-Dimethyl-4-(methylamino)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one hydrochloride | [EINECS(EC#)]
208-281-3 | [Molecular Formula]
C12H15N3O | [MDL Number]
MFCD16620361 | [MOL File]
519-98-2.mol | [Molecular Weight]
217.27 |
| Chemical Properties | Back Directory | [Melting point ]
50-53°C | [Boiling point ]
324.5±45.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.76±0.20(Predicted) | [color ]
Pale Yellow to Brown |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Orange Low Melting Waxy Solid | [Uses]
A metabolite of Dipyrone | [Definition]
ChEBI: A member of the class of pyrazoles that is antipyrine substituted at C-4 by a methylamino group. It is a metabolite of aminopyrine and of metamizole. | [in vivo]
The aim of this study is to assess the pharmacokinetics of its active metabolites 4-Methylamino antipyrine in male piglets after a single intramuscular injection of Metamizole. Eight healthy male piglets are administered Metamizole (100 mg/kg) intramuscularly. 4-Methylamino antipyrine plasma concentrations are quantitatively detectable from 0.25 to 48 h. The average maximum concentrations of 4-Methylamino antipyrine is of 47.59 mg/mL. The average half-lives is 8.57 h for 4-Methylamino antipyrine[1]. |
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